Turning Aspirin into Tylenol

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Published 2018-04-08
This is a video that I've been meaning to make for a while. I think the idea of converting one drug to another is a pretty cool concept.

About a year ago, I made a series where I chemically converted Aspirin to Tylenol (aka acetaminophen, paracetamol, or APAP). The original series was spread out over several videos and was over 90 minutes long. It has a lot more detail, but it was a much bigger commitment to watch.

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Nile talks about lab safety:    • Chemistry is dangerous.  

Music in credits (Walker by SORRYSINES): soundcloud.com/sorrysines/walker

All Comments (21)
  • @marcusmerrin192
    I'm an old-school chemist (PhD 1987). I love what you do, and it reminds me why I fell in love with chemistry as a teenager! Keep experimenting and teaching!
  • @TrueVartoc
    "I was able to convert 200 extra strength aspirins into one really weak tylenol" SUCCESS
  • @maol2038
    “Polymerized crap” is the IUPAC name
  • @Xypos
    NileRed: The process is very straight forward Me 26 minutes later: Wait what?
  • I followed along with your video precisely and I ended up with 42 pounds of crystal methamphetamine. Please advise.
  • "Ah crap I got aspirin, not tylenol" "Don't worry mom, I can work with this"
  • @gl1500ctv
    21:36 I thought "he's good... look, there's a Tylenol capsule in the product!" It was his stir bar.
  • I have to admit, I use your videos to fall asleep at night. Your voice is so soothing, calm, clear, and never talk too fast. You could narrate a bus schedule, and I'd buy the audiobook. I listen intently and usually before you're done, I am out like a light. But you are not boring! Thats how I discovered your channel. I actually watch the video again the next day. Thanks for your excellent channel!
  • @bernard2735
    Note: The "filler junk" is actually a carefully designed matrix that produces the correct dissolution profile and bio-availability of the tablet, whilst also ensuring proper binding, distribution of active in the matrix, good compression and ejection from the tablet press, etc., all without having a biologically active impact.
  • @rosycat4254
    I have no clue what come out of his mouth 99% of the time, but his videos are really addicting to watch
  • @zoogoo404
    I watched the original videos a while back. This was far less scattershot and easier to digest.
  • @purgruv
    Thanks, but I think my headache has gone now…
  • @culgi
    I like to imagine NileRed as an alchemist in a fantasy world. "Today, I will be turning this stone into a bar of iron." or "I had an idea to try to turn a healing potion into a poison."
  • @RobotHunter1234
    next time someone asks me for a tylenol imma whip out my bottles of aspirin and my chemistry set and make it from scratch just to spite them
  • @mheermance
    Only being off by an order of magnitude isn't bad, if you are an astronomer.
  • @FreezeAU
    The “polymerized crap” label in the diagram at 7:44 made me laugh way more than it ought to have 🤣
  • @ClassickXD
    My sister's going to school for chemistry. I always whip out somthing I've learned from these vidoes. Her face is priceless