Pharmacology - HYPERTENSION & ANTIHYPERTENSIVES (MADE EASY)

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Published 2017-03-21
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Antihypertensives are a class of drugs that are used to treat hypertension. Antihypertensive therapy seeks to prevent the complications of high blood pressure such as heart attack and stroke. This pharmacology lecture covers topics such as pathophysiology of hypertension, regulation of blood pressure, cardiac output, systemic vascular resistance, baroreceptors, alpha & beta receptors, vasoconstriction, vasodilation, renin-angiotensin-aldosterone system, bradykinin, nitric oxide. Mechanism of action of antihypertensive drugs and their side effects; adrenergic antagonists; alpha & beta blockers, centrally acting adrenergic agents, dihydropyridine & nondihydropyridine calcium channel blockers, loop, thiazide, potassium-sparing diuretics, renin inhibitors, angiotensin converting enzyme (ACE) inhibitors, angiotensin II receptor type 1 blockers (ARBs), endothelin receptor antagonist, dopamine-1 receptor agonist, peripheral vasodilators. Drugs mentioned include; Doxazosin, Prazosin, Clonidine, Methyldopa, Amlodipine, Felodipine, Nicardipine, Nifedipine, Diltiazem, Verapamil, Furosemide, Hydrochlorothiazide, Triamterene, Spironolactone, Aliskiren, Benazepril, Captopril, Enalapril, Lisinopril, Quinapril, Ramipril, Candesartan, Irbesartan, Losartan, Olmesartan, Valsartan, Bosentan, Fenoldopam, Sodium Nitroprusside, Nitroglycerin, Hydralazine, and Minoxidil.

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0:00 Pathophysiology of hypertension
2:55 Alpha-1 blockers
3:10 Beta blockers
4:01 Centrally-acting adrenergic drugs
4:49 Calcium channel blockers
7:27 Diuretics
8:57 Inhibitors of renin-angiotensin-aldosterone system
12:25 Miscellaneous antihyperten

All Comments (21)
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    Your videos deserve more views and likes! Thank you for putting the effort into it and for simplifying this topic.
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  • @Qi33Qi
    Thank you so much for this video! It's been years since my cardiology module and This is a great refresher :)
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  • This really helps with understanding rather than memorizing. Thank you!
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  • @panatypical
    This is a very useful refresher presentation for me, since I have been taking combinations of these medications for a number of years. Understanding their mechanisms of action often allows me to identify causation of changes in my conditions. I can then communicate more intelligently with my physicians.
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