Mitochondria - The Key To Disease and Mental Health with Dr. Martin Picard

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Published 2023-08-17
Emerging evidence suggests mitochondrial dysfunction can cause or contribute to many psychiatric and neurologic disorders. To promote metabolic and mental health, it’s crucial to better understand mitochondria and what we can do to keep them healthy.

As Dr. Martin Picard explains, mitochondria are small components of cells that are involved in just about every disease process, and by extension, in every aspect of promoting health. Since mitochondria are where we transform food energy into energy our bodies use, it makes sense why they are so important for health and longevity. Dr. Picard from Columbia University is one of the most prominent mitochondrial researchers, and he joins us to discuss all things mitochondria-related – from the basics of what mitochondria are and how they function, to the three most important things we can do to keep our mitochondria healthy.

Expert featured in this video
Martin Picard, PhD
www.picardlab.org/
Twitter @MitoPsychoBio

0:00 Introduction to Dr. Martin Picard
3:16 What Are Mitochondria and Where Are They?
9:04 Ecosystem of Mitochondria
10:25 Mitochondria and Disease
16:38 Genetics and Mitochondria
19:18 Lifestyle Choices for Poor Mitochondrial Health
22:08 Impact of Psychological States on Mitochondria
25:55 Medications and Mitochondrial Dysfunction
32:12 How to Improve Mitochondrial Function
52:29 Conclusion

Link to Dr. Picard's talk from the inaugural Metabolic Psychiatry Conference in 2022
   • Mitochondria in Physical and Mental H...  

The Human Psychobiology Project
www.humanpsychobiology.org/

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All Comments (21)
  • @kdbin101-1
    Tips from Dr Picard: 1. Move! Exercise encourages your body to produce new mitochondria (up to 2x) 2. Don’t eat too much, it’s ok to be hungry - intermittent fasting is great for your mitochondria 3. A new idea being proposed is possibly your mental state can change your mitochondria (ie., do what you can to lead a life that makes you happy!)
  • @user-sb3wh3dd4v
    1- move more. 2- eat less. 3- be happy, positive... which requires adequate sleep.
  • When I was 10 I learned about mitochondria. I was hooked! The mitochondria is my favorite organelle
  • @davida1606
    Where would we be without nerds! Thank God for their exuberance and passion for their work! Wonderful.
  • @yl1487
    Finally a person who can discuss mitochondria without finding themselves saying 'mitochondria .... make energy' and appropriately describes them as transforming energy.
  • @mykiemon
    He's so right that medicine has to move to understanding and fixing problems per the individual rather than "batch" solutions. This is ongoing and gathering steam.
  • @KetoMama777
    1= move exercise 2= dont eat so much 3= stay positive
  • @KarmaMechanic988
    PhD biochemist emergency physician here. Read about alpha lipoic acid and acetyl N carnitine as a combination. In vitro the combination are the mitochondria's best friend s. Just need some good studies in people!
  • @campbellpaul
    I have been meditating for many, many decades, and have used visualization as well as breathing techniques in conjunction with adequate exercise, nutrition and healthy sleeping habits. I discovered visualization of healthy, long mitochondria is very essential to staying healthy and fit (I am 52). Concentrating on the digestive system, and the brain are essential if you want to increase your physical and mental health as well as draw positivity into your life. The key to spiritual, mental and physical well-being is recognizing and visualizing the same science that we obtain in the form of products and healthy regimens, and it shouldn't be left out. Visualization is the the missing puzzle piece to our completeness.
  • @lilytea3
    0:04: 🧬 Dr. Martin Picard discusses the importance of mitochondria in metabolic and mental health. 4:07: 🧠 Mitochondria are like the brain of the cell, involved in transforming energy and processing information. 9:35: 💡 Mitochondria transform energy from food and oxygen into different forms of energy, such as ATP, which powers human function and consciousness. 14:39: 💡 Metabolic dysfunction, including insulin resistance, can impact mitochondria and energy flow in the body. 19:53: 🔬 The video discusses acquired mitochondrial disorders and how they can be influenced by psychological states, chronic stress, early life adversity, diet, and exposure to insecticides and pesticides. 25:12: 💡 Communication between the brain and body is energetically demanding, and mitochondrial biology plays a crucial role in this energetic connection. 30:20: 🧠 Psychiatry should focus on short-term acute episodes of psychosis and explore alternative methods to target mitochondrial health for long-term treatment. 35:50: 🏃‍♂ Physical activity stimulates the production of more mitochondria, which can improve energy levels and overall health. 40:35: 🔑 Individualized medicine, moderation in eating, and positive psychological states can promote mitochondrial health. 45:15: 🧠 Feeling positive and having positive experiences can improve mitochondrial biology in immune cells and potentially in brain cells. 50:39: 🧠 The speaker believes that the current framework for understanding mental health is overhyped and disempowering, and suggests an alternative framework that respects individual differences. Recap
  • @mariahrossi3072
    One thing I did not hear in this video was the role of sunshine. I have been hearing a lot about the role of infrared light in melatonin production and melatonin is an antioxidant in the mitochondria.
  • @JessicaSilva-pu5hj
    Methylene blue.. started for mother with alzheimers...lots of improvements...it's helped with mitochondria health, regulated neurotransmitters so is excellent...discontinued psychotic drugs..her speech started coming back..excellent awareness...accepting lots of new healthy foods...also discontinued sleeping pill..sleeps 8 to 9 hours on her own
  • @petercyr3508
    I think there are 2 main things that hurt mitochondtia: -burning glucose most or all of the time. This happens whenever you consume glucose, you know, carbs. Your body has to process consumed carbs before it can use fat. -Eating and processing food constantly. Eat 1 or 2 low carb meals. Not 6 meals. Be a fat burner producing ketones. Practice time restricted eating and extended fasting to induce autophagy to repair and rebuild mitochondria.
  • @CashMoneyMoore
    The powerhouse of the ... brain, immune system, emotional health, neurological health, cardiovascular health
  • @dzdxdd
    Cancer begins when the mitochondria of a cell become so damaged they can't carry out oxidative phosphorylation, but instead of dying the cell manages to switch to the fermentation of glucose in the cytoplasm.
  • @karenmarvin6052
    This is an absolutely wonderful explanation of mitochondria. Thank you. Please give us more!
  • @user-xv1zr4ln7l
    Interesting! My energy levels are often not too good, since my diet is not ideal and I do not take enough physical exercise. However, I have seen in my life many, many times that when I am suddenly able to fulfill my calling, I immediately feel energized and I forget about the tiredness.
  • @Fomites
    Your ten-year-old learning about mitochondria? At that age we didn't even know about cells. Born in 1952 Sydney Australia :-)
  • @jimlambrick4642
    I'd add daily exposure to sunlight. Not burning, not tanning, just natural level on the skin sunlight. We're not designed to live indoors in cocoons.