Dr. Chris Knobbe - 'Are Vegetable Oils the primary driver of Obesity, Diabetes and Chronic Disease?'

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Published 2023-12-16
Dr. Chris Knobbe is a physician, researcher, ophthalmologist, public health advocate, and Associate Clinical Professor Emeritus, formerly of the University of Texas Southwestern Medical Center in Dallas, Texas. He is known primarily for his research, publications, and presentations connecting Westernised diets and highly polyunsaturated vegetable oils to numerous chronic diseases, including coronary heart disease, hypertension, stroke, cancers, type 2 diabetes, metabolic syndrome, obesity, Alzheimer’s disease, autoimmune diseases, and age-related macular degeneration (AMD).

Dr. Knobbe’s research has focused greatly on the “vegetable oil hypothesis” as the primary driver of overweight and chronic disease. In 2016 he formally introduced the hypothesis that processed foods and vegetable oils are the primary drivers of AMD, which is the leading cause of irreversible vision loss and blindness in people over the age of 50, worldwide. Dr. Knobbe has presented his research on ancestral dietary strategy and macular degeneration at various conferences and has also authored a book titled 'The Ancestral Diet Revolution: How Vegetable Oils and Processed Foods are Destroying Your Health'. His research suggests that macular degeneration can be prevented and treated through an ancestral dietary strategy and “sacred” foods.

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All Comments (21)
  • @aliciamarana
    US citizen here, I took my kids shopping with me yesterday. (12 and 15) Anything they wanted to put in the cart, they had to read the ingredients and if there was a seed oil in it, they couldn’t have it. My 15yo was stunned by the number of “foods” that were laced with poisonous oils. We came home with meat, eggs, dairy and some fruit. Actually, also a box of strawberry creamsicle type frozen dessert bars made in Mexico. The US just wants to poison us all near enough to death that we buy all the drugs to keep us”living”. Thank you doctor for the research! Keep fighting the good fight!
  • @curiouskitten
    I stopped eating out! Even the expensive/classy restaurants use cheapest ingredients. I can feel it next day!
  • @carbaum7549
    I'm in my late 20s and for years I've had unusually high blood pressure, typically around 145/90. I'm overweight at 240lbs. I stumbled onto this video purely by chance, but I've adjusted my diet according to it. It's not even been a week now, and for the first time in my adult life, I recorded a blood pressure of 125/79. I've never seen it below 135. My inflammation has decreased notably, and my sleep has been incredible these past couple nights. I finally know how to heal my body! I'll check back on this with weight loss results later! :D - Thank you, Dr. Knobbe!
  • The wife and I both late 50s. Been eating wrong all our lives. She's got breast cancer, I was morbidly obese with T2D. I've turned it around on Carnivore but cancer is harder to defeat. The worst thing is watching the next generation destroy themselves on a fast food, seed oil based diet. Take away pizzas, burgers and french fries are so much more convenient than having to make the effort to eat the Proper Human Diet.
  • @craigwillms61
    Since I've learned about seed oils about 3 years ago I've changed my diet. Olive oil, butter, and coconut oil are what I use in the kitchen, and I avoid restaurants the best I can - within reason. My health has improved markedly and I'm down 20lbs - so, yes, I'm convinced.
  • @gailascari
    Stopped cooking with seed oils after I realized every time I cooked with such oils I got terrible stomach ache. Now I only use olive oil and butter at home. I remain in great health & low end of normal weight for height, cycle to work 10 km a day. On zero medications & I am old enough to retire. 😊
  • I am sharing this in the hope that it motivates someone to act sooner than I did. I got sensible with sugar and carbs, and quit 7 very common things altogether - 1) anything battered and fried, 2) bread, 3) pasta, 4) potatoes, 5) corn, 6) rice, and 7) all fruits but rasberries, blueberries and strawberries. Plus, the only deserts I eat are an occassional bit of sugar free jello or pudding, sprinkled with nuts and a bit of whipped cream. This isn't a true KETO diet, but it's along those lines, and the 7 things I listed were the main staples of my unhealthy diet. I also replaced seed oils with butter, lard, bacon grease and olive oil. I eat all the meats of every kind I want, as long as they are not fried in seed oil, along with lots of eggs, cheese and low carb veggies. Bacon is wonderful, and I eat LOTS of it. Three months after I started this, my doctor took me off all T2D meds, as I no longer needed them. Two years later, I have lost 35 pounds and my cholesterol and triglycerides are perfectly normal for the first time in my life. {My overall cholesterol after fasting was once 600, and my triglycerides were 1400 - seriously.) My heart checkups have also improved exponentially. Wish me luck, and please do not wait . Start a more healthy diet today.
  • @Jenna-rl4cu
    Thank you Dr Knobbe, first I wouldn't trust any words from Harvard now! I live in MA. I feel so much better not eating seed oils. My Rheumatoid Arthritis is under control, my gut, no IBS. My diet is 90% meat based and at 64 feel better than I did in my thirties. I've had the same eye prescription for three years. My doctor us surpried🎉. Again thank you!
  • @paltek149
    demonizing saturated fat and cholesterol made the people to go for seed oil.
  • @peterweeden6203
    Thankyou Dr Knobbe, this presentation has turned my head. I have been aware of the dangers of seed oil consumption, but had primarily focussed on sugars and carbohydrates to be the main drivers of metabolic disregulation. An essential adjustment of thinking was needed, and this presentation has provided sufficient, quantified and qualified information for me to do so. Thankyou once again.
  • @gastropodahimsa
    There is one thing that I haven't heard mentioned in this line of reasoning that I think is worth considering. All of the vegetable oils that are used for frying, especially in restaurants, are treated with strong synthetic antioxidants because they have to be, otherwise they wouldn't even last a few hours in the fryer. Those antioxidants are, of course, oil soluble, and are eaten with whatever food has been cooked in the oil. They are formulated to resist degradation even in the harsh conditions of industrial frying and are certainly resistant to biological/human-enzymatic degradation, and so they must end up dissolved in the fats of human cells, both storage fat and structural. The nature of the antioxidants is to inhibit chemical changes to fats and they must continue to do that in the body. That is metabolic havoc for sure.
  • @toni4729
    I know this may have been asking too much but, I'm concerned for the vegetarian population in India that have recently turned to oils and have left butter and ghee behind. I understand this has become quite a problem.
  • @biodivers5294
    Cristal clear! The struggle between carnivores and vergetarians is not worth the fight, we have to to fight processed food (that isn’t food at all). Thank you voor your persistance in pointing this out!
  • @heatherclark8668
    Those stubborn old buzzards who refused to cut down on bacon butter and red meat were right after all
  • @carnigoth
    I wish Dr. Knobbe would be invited to Hubermann lab and other big podcasts. I hope his message gets the attention we need
  • @GSH-vg3wf
    Great talk. I have been avoiding seed oils since 2017. Over that time, I have maintained a 30 lb weight loss eating a low carb real food diet.
  • @karend.9218
    I’m fair skin and burn easy. I don’t tan, i freckle. 2018 went low carb high healthy fat. 1 year later noticed I don’t burn as quickly in summer sun exposure, w/o sunscreen. Thought it was weird, but seed oils do not comprise my cells anymore and it made a huge difference.
  • Four years ago I started intermittent fasting and became keto and after a few month carnivore. A few month later my mother also started fasting and ate low carb because she saw how well it worked for me. She lost weight, improved prediabetes and high blood pressure. But she still had seed oils back then. Two years ago she told me about her macular degenaration. I told her about your presentations and that she should stop eating seed oils and margerine (she does't understand English well enough, so I could't really show her your talks) But she listened to me (probably also because her mother is almost blind and had margerine and seed oils most her life) and cut out all seed oils, which was hard for her because she never ate butter and is not a dairy fan. But one year later when she had her next eye exam the doctor was stunned. He could't believe that her macular degenaration could improve. But it was what the eye exam showed. He never saw that before. 😊Now she doesen't even need her eye drops anymore. When people ask me why I am not eating seed oils and I don't let my kids eat french fries etc. I tell them I am too afraid of getting blind. I also think lipomas might be related to seed oil intake. I have some of them. After cutting out seed oils I didn't get new lipomas. It is also as if my lipomas shrinked a little, but they are still there... I wonder if there is research about lipomas and seed oil intake and if it is possible to reverse lipomas by diet only. 😊
  • @user-kk1ru9cv7w
    ITS NOT A HYPOTHESIS ANYMORE. I SAVED MY LIFE SWITCHED TO BEEF TALLOW.
  • @sheilam4964
    Thx for doing this, filming it and sharing it with us. 👍👍👍👍👍